Callyazepin and (3R)-Methylazacyclodecane, Nitrogenous Macrocycles from a Callyspongia sp. Sponge.

@article{Kim2016CallyazepinA,
  title={Callyazepin and (3R)-Methylazacyclodecane, Nitrogenous Macrocycles from a Callyspongia sp. Sponge.},
  author={Chang-Kwon Kim and Jung-Kyun Woo and Yeon-Ju Lee and Hyi-Seung Lee and Chung Ja Sim and Dong‐Chan Oh and Ki-bong Oh and Jongheon Shin},
  journal={Journal of natural products},
  year={2016},
  volume={79 4},
  pages={
          1179-83
        }
}
Callyazepin (1) and (3R)-methylazacyclodecane (2), nitrogenous macrocycles, were isolated from a tropical Callyspongia sp. sponge. The combined spectroscopic analyses revealed that the structure of 1 is a bicyclic azepane ammonium salt of a novel structural class derived from mixed biogenetic origins. The configuration of the whole molecule and the conformation of the formamide group were assigned by proton-proton coupling constants, a NOESY analysis, and the application of the phenylglycine… 
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