Call for an enzyme genomics initiative

@article{Karp2004CallFA,
  title={Call for an enzyme genomics initiative},
  author={Peter D. Karp},
  journal={Genome Biology},
  year={2004},
  volume={5},
  pages={401 - 401}
}
I propose an Enzyme Genomics Initiative, the goal of which is to obtain at least one protein sequence for each enzyme that has previously been characterized biochemically. There are 1,437 enzyme activities for which Enzyme Commission (EC) numbers have been assigned but no sequence can be found in public protein-sequence databases. 

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