Calibrating the Mitochondrial Clock

@article{Gibbons1998CalibratingTM,
  title={Calibrating the Mitochondrial Clock},
  author={A. Gibbons},
  journal={Science},
  year={1998},
  volume={279},
  pages={28 - 29}
}
DNA studies of the remains of the last Russian tsar, Nicholas II illustrate troubling questions in forensics and the dating of evolutionary events. The Tsar inherited two different sequences of mitochondrial DNA (mtDNA) from their mother, a condition known as heteroplasmy that was previously considered rare but which new studies show may occur in at least 10% and probably 20% of all humans. This may mean that mtDNA mutates perhaps as much as 20-fold faster than expected, according to two… Expand
56 Citations
Recombination or mutation rate heterogeneity? Implications for Mitochondrial Eve.
  • 69
Molecular clocks: when times are a-changin'.
  • 355
  • PDF
Genetic analysis of early holocene skeletal remains from Alaska and its implications for the settlement of the Americas.
  • 206
  • PDF
Prolonged decay of molecular rate estimates for metazoan mitochondrial DNA
  • 26
  • Highly Influenced
  • PDF
GENETICS OF MODERN HUMAN ORIGINS AND DIVERSITY
  • 103
  • PDF
GENETIC DRIFT IN RECENT HUMAN EVOLUTION?
  • 6
  • PDF
Inherited Variability of the Mitochondrial Genome and Successful Aging in Humans
  • 74
African Eve: Hoax or Hypothesis?
  • 5
  • PDF
African Haplogroup L mtDNA sequences show violations of clock-like evolution.
  • 50
  • PDF
...
1
2
3
4
5
...