Calf serum constituent fractions influence polyethylene wear and microbial growth in knee simulator testing.

@article{Brandt2012CalfSC,
  title={Calf serum constituent fractions influence polyethylene wear and microbial growth in knee simulator testing.},
  author={J M Brandt and Kory D J Charron and L. G. Zhao and Steven J. Macdonald and John B. Medley},
  journal={Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine},
  year={2012},
  volume={226 6},
  pages={
          427-40
        }
}
Calf serum lubricants consisting of various polypeptide constituent fractions are routinely used in knee wear simulators as part of the standardized test protocol. Three calf sera (bovine, new-born and alpha) were diluted as per the recommendation of ISO 14243-3 and used in displacement-controlled knee wear simulators to investigate their effects on polyethylene wear. Biochemical analyses included measuring total polypeptide degradation, electrophoretic profiles and low-molecular weight… CONTINUE READING
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