Calditol-linked membrane lipids are required for acid tolerance in Sulfolobus acidocaldarius

@article{Zeng2018CalditollinkedML,
  title={Calditol-linked membrane lipids are required for acid tolerance in Sulfolobus acidocaldarius},
  author={Z. Zeng and Xiao-Lei Liu and Jeremy H. Wei and R. Summons and P. Welander},
  journal={Proceedings of the National Academy of Sciences},
  year={2018},
  volume={115},
  pages={12932 - 12937}
}
Significance It is thought that the distinct ether lipid membranes of archaea allow them to thrive in environmental extremes. However, it has been difficult to demonstrate this physiological role directly. Here, we identify a protein required for the biosynthesis of a unique archaeal lipid head group, calditol, whose production was considered to be restricted to a subset of archaeal thermoacidophiles. We show that deletion of this protein in Sulfolobus acidocaldarius prevents production of… Expand
Energy flux controls tetraether lipid cyclization in Sulfolobus acidocaldarius
Energy flux controls tetraether lipid cyclization in Sulfolobus acidocaldarius.
Multiple environmental parameters impact lipid cyclization in Sulfolobus acidocaldarius.
The Cell Membrane of Sulfolobus spp.—Homeoviscous Adaption and Biotechnological Applications
GDGT cyclization proteins identify the dominant archaeal sources of tetraether lipids in the ocean
The structures of two archaeal type IV pili illuminate evolutionary relationships
Physiological Characterization of Sulfolobus acidocaldarius in a Controlled Bioreactor Environment
...
1
2
...

References

SHOWING 1-10 OF 62 REFERENCES
From Promiscuity to the Lipid Divide: On the Evolution of Distinct Membranes in Archaea and Bacteria
  • Y. Koga
  • Biology, Medicine
  • Journal of Molecular Evolution
  • 2014
Archaeal phospholipids: Structural properties and biosynthesis.
  • A. Caforio, A. Driessen
  • Biology, Medicine
  • Biochimica et biophysica acta. Molecular and cell biology of lipids
  • 2017
Biosynthesis of Ether-Type Polar Lipids in Archaea and Evolutionary Considerations
  • Y. Koga, H. Morii
  • Biology, Medicine
  • Microbiology and Molecular Biology Reviews
  • 2007
Lipids of Thermoplasma acidophilum.
Sulfolobus: A new genus of sulfur-oxidizing bacteria living at low pH and high temperature
Expanding the Limits of Thermoacidophily in the Archaeon Sulfolobus solfataricus by Adaptive Evolution
...
1
2
3
4
5
...