Calculating clinically relevant drug doses to use in animal studies

Abstract

Dear Editor, We thank Dr. Pierre J. Marie for his interest in our recent study demonstrating that strontium ranelate (SrR) does not stimulate bone formation in ovariectomized (OVX) rats [1], and we appreciate this opportunity to respond. SrR has been found to be effective in reducing nonvertebral [2, 3] and vertebral [3–5] fractures in postmenopausal women… (More)
DOI: 10.1007/s00198-008-0741-9

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1 Figure or Table