Calcium waves in astrocytes-filling in the gaps.

  title={Calcium waves in astrocytes-filling in the gaps.},
  author={S Finkbeiner},
  volume={8 6},
Stimulus-evoked cellular responses are sometimes organized in the form of propagating waves of cytoplasmic Ca2+ increase. Ca2+ waves can be elicited in cultured astrocytes by the neurotransmitter glutamate; however, the propagation mechanism is unknown. Here, qualitative and quantitative features of propagation suggest that astrocytic Ca2+ waves are mediated by an intracellular signal that crosses intercellular junctions. The role of gap junctions in cell-cell Ca2+ wave propagation was… CONTINUE READING
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