Calcium upregulated survivin expression and associated osteogenesis of normal human osteoblasts.

@article{Ortiz2012CalciumUS,
  title={Calcium upregulated survivin expression and associated osteogenesis of normal human osteoblasts.},
  author={Jan Ortiz and Laisheng Lee Chou},
  journal={Journal of biomedical materials research. Part A},
  year={2012},
  volume={100 7},
  pages={
          1770-6
        }
}
Survivin is an antiapoptotic protein expressed in all phases of the normal cell cycle but is at its highest level during the G2/M interphase. This protein has been recently identified in normal human osteoblasts and has raised questions about the regulation of its expression. This study intends to verify if survivin expression could be manipulated by external factors such as calcium ions. Normal human alveolar bone explants recovered from six healthy donors were cultured to 2nd passage. Cells… CONTINUE READING

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