Calcium tolerance of isolated rat heart cells.

@article{Altschuld1980CalciumTO,
  title={Calcium tolerance of isolated rat heart cells.},
  author={Ruth A. Altschuld and L. Gibb and A Z Ansel and Charlene M. Hohl and Fred A. Kruger and Gerald P. Brierley},
  journal={Journal of molecular and cellular cardiology},
  year={1980},
  volume={12 12},
  pages={
          1383-95
        }
}
Abstract Freshly isolated adult rat heart cells, which initially show the elongated, rod-shaped morphology typical of heart cells in situ , are almost quantitatively converted to rounded contracture forms by exposure to 1 m m Ca 2+ . These Ca 2+ -sensitive cells became Ca 2+ -tolerant following a short period of metabolic activity in a low-Ca 2+ medium, in that they retain their rod-shaped configuration when challenged with Ca 2+ after this preincubation step. Tolerance to Ca 2+ develops in… CONTINUE READING

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