Calcium supplements for the prevention of colorectal adenomas. Calcium Polyp Prevention Study Group.

@article{Baron1999CalciumSF,
  title={Calcium supplements for the prevention of colorectal adenomas. Calcium Polyp Prevention Study Group.},
  author={John A. Baron and Marie Beach and Jack S. Mandel and Rosalind U van Stolk and Robert W Haile and Robert S. Sandler and Richard I. Rothstein and Robert W. Summers and Dale C. Snover and Gerald J. Beck and John H. Bond and E. Robert Greenberg},
  journal={The New England journal of medicine},
  year={1999},
  volume={340 2},
  pages={101-7}
}
BACKGROUND AND METHODS Laboratory, clinical, and epidemiologic evidence suggests that calcium may help prevent colorectal adenomas. We conducted a randomized, double-blind trial of the effect of supplementation with calcium carbonate on the recurrence of colorectal adenomas. We randomly assigned 930 subjects (mean age, 61 years; 72 percent men) with a recent history of colorectal adenomas to receive either calcium carbonate (3 g [1200 mg of elemental calcium] daily) or placebo, with follow-up… CONTINUE READING

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