Calcium sparks in smooth muscle.

@article{Jaggar2000CalciumSI,
  title={Calcium sparks in smooth muscle.},
  author={Jonathan H Jaggar and Valerie A Porter and W. Jonathan Lederer and Mark T. Nelson},
  journal={American journal of physiology. Cell physiology},
  year={2000},
  volume={278 2},
  pages={C235-56}
}
Local intracellular Ca(2+) transients, termed Ca(2+) sparks, are caused by the coordinated opening of a cluster of ryanodine-sensitive Ca(2+) release channels in the sarcoplasmic reticulum of smooth muscle cells. Ca(2+) sparks are activated by Ca(2+) entry through dihydropyridine-sensitive voltage-dependent Ca(2+) channels, although the precise mechanisms of communication of Ca(2+) entry to Ca(2+) spark activation are not clear in smooth muscle. Ca(2+) sparks act as a positive-feedback element… CONTINUE READING
Highly Influential
This paper has highly influenced 19 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS

Citations

Publications citing this paper.
Showing 1-10 of 252 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 225 references

Similar Papers

Loading similar papers…