Calcium silicate/calcium phosphate biphasic cements for vital pulp therapy: chemical-physical properties and human pulp cells response

@article{Gandolfi2015CalciumSP,
  title={Calcium silicate/calcium phosphate biphasic cements for vital pulp therapy: chemical-physical properties and human pulp cells response},
  author={M G Gandolfi and Gianrico Spagnuolo and F Siboni and Alfredo Procino and Virginia Rivieccio and Gian Andrea Pelliccioni and C Prati and Sandro Rengo},
  journal={Clinical Oral Investigations},
  year={2015},
  volume={19},
  pages={2075-2089}
}
The aim was to test the properties of experimental calcium silicate/calcium phosphate biphasic cements with hydraulic properties designed for vital pulp therapy as direct pulp cap and pulpotomy. CaSi-αTCP and CaSi-DCDP were tested for ion-releasing ability, solubility, water sorption, porosity, ability to nucleate calcium phosphates, and odontoblastic differentiation—alkaline phosphatase (ALP) and osteocalcin (OCN) upregulation—of primary human dental pulp cells (HDPCs). The materials showed… CONTINUE READING