Calcium signaling in the developing Xenopus myotome.

@article{Ferrari1999CalciumSI,
  title={Calcium signaling in the developing Xenopus myotome.},
  author={M. Belicchi Ferrari and Nicholas C. Spitzer},
  journal={Developmental biology},
  year={1999},
  volume={213 2},
  pages={
          269-82
        }
}
Embryonic Xenopus myocytes generate spontaneous calcium (Ca(2+)) transients during differentiation in culture. Suppression of these transients disrupts myofibril organization and the formation of sarcomeres through an identified signal transduction cascade. Since transients often occur during myocyte polarization and migration in culture, we hypothesized they might play additional roles in vivo during tissue formation. We have tested this hypothesis by examining Ca(2+) dynamics in the intact… CONTINUE READING
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