Calcium sensitization mechanisms in detrusor smooth muscles

@article{Anjum2018CalciumSM,
  title={Calcium sensitization mechanisms in detrusor smooth muscles},
  author={Irfan Anjum},
  journal={Journal of Basic and Clinical Physiology and Pharmacology},
  year={2018},
  volume={29},
  pages={227 - 235}
}
  • Irfan Anjum
  • Published 27 June 2018
  • Biology
  • Journal of Basic and Clinical Physiology and Pharmacology
Abstract The contraction of detrusor smooth muscles depends on the increase in intracellular calcium. The influx of calcium from the plasma membrane calcium channels and calcium release from the sarcoplasmic reticulum give rise to intracellular calcium. Under the pathophysiological conditions, the increased sensitivity of regulatory and contractile proteins to calcium also plays an important role in maintaining the spontaneous detrusor smooth muscle activity. Many proteins have been identified… 

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