Calcium-sensing receptor in the brain.

  title={Calcium-sensing receptor in the brain.},
  author={Shozo Yano and Edward Meigs Brown and Naibedya Chattopadhyay},
  journal={Cell calcium},
  volume={35 3},
Following its cloning through an homology-based method from a rat striatal library, the calcium-sensing receptor (CaR) has been localized in the brains of adult and developing rats by immunocytochemistry and in situ hybridization with CaR-specific antibodies and cDNA probes, respectively. The receptor resides in numerous regions of the brain at widely varying levels. The highest levels are present within the subfornical organ (SFO) and the olfactory bulbs. Substantial levels of expression are… CONTINUE READING


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