Calcium-ryanodine receptor complex. Solubilization and partial characterization from skeletal muscle junctional sarcoplasmic reticulum vesicles.

@article{Pessah1986CalciumryanodineRC,
  title={Calcium-ryanodine receptor complex. Solubilization and partial characterization from skeletal muscle junctional sarcoplasmic reticulum vesicles.},
  author={Isaac N Pessah and Andrea Francini and Donald J. Scales and Andrew L Waterhouse and John E. Casida},
  journal={The Journal of biological chemistry},
  year={1986},
  volume={261 19},
  pages={8643-8}
}
The Ca2+-ryanodine receptor complex is solubilized in functional form on treating sarcoplasmic reticulum (SR) vesicles from rabbit fast skeletal muscle with 3-[(3-cholamidopropyl)dimethylammonio]-1-propane-sulfonate (CHAPS) (1 mg/mg protein) and 1 M NaCl at pH 7.1 by shaking for 30 min at 5 degrees C. The heavy membrane preparations obtained from… CONTINUE READING