Calcium plus vitamin D supplementation and the risk of fractures.

@article{Jackson2006CalciumPV,
  title={Calcium plus vitamin D supplementation and the risk of fractures.},
  author={Rebecca D. Jackson and Andrea Z LaCroix and Margery Gass and Robert B. Wallace and John Robbins and Cora E. Lewis and Tamsen L. Bassford and Shirley A. A. Beresford and Henry R. Black and Patricia Lanoie Blanchette and Denise E. Bonds and Robert L. Brunner and Robert G. Brzyski and Bette Jane Caan and Jane A. Cauley and Rowan Chlebowski and Steve Cummings and Iris A. Granek and J. K. Hays and Gerardo Heiss and Susan Lee Hendrix and Barbara V Howard and Judith Hsia and F. Allan Hubbell and Karen C Johnson and Howard L Judd and Jane Morley Kotchen and Lewis H. Kuller and Robert D. Langer and Norman L. Lasser and Marian C. Limacher and Shari Ludlam and Joann E. Manson and Karen L. Margolis and Joan McGowan and Judith K. Ockene and Michael O'Sullivan and Lawrence S. Phillips and Ross L. Prentice and Gloria E. Sarto and Marcia L. Stefanick and Linda J Van Horn and Jean Wactawski-Wende and Evelyn A Whitlock and Garnet L. Anderson and Annlouise R. Assaf and David Barad},
  journal={The New England journal of medicine},
  year={2006},
  volume={354 7},
  pages={
          669-83
        }
}
BACKGROUND The efficacy of calcium with vitamin D supplementation for preventing hip and other fractures in healthy postmenopausal women remains equivocal. METHODS We recruited 36,282 postmenopausal women, 50 to 79 years of age, who were already enrolled in a Women's Health Initiative (WHI) clinical trial. We randomly assigned participants to receive 1000 mg of elemental [corrected] calcium as calcium carbonate with 400 IU of vitamin D3 daily or placebo. Fractures were ascertained for an… CONTINUE READING
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