Calcium phosphates compounds in conjunction with hydrogel as carrier for BMP-2: a study on ectopic bone formation in rats.

@article{HulsartBillstrm2011CalciumPC,
  title={Calcium phosphates compounds in conjunction with hydrogel as carrier for BMP-2: a study on ectopic bone formation in rats.},
  author={Gry Hulsart-Billstr{\"o}m and Qinghong Hu and Kristoffer Bergman and Kenneth B. Jonsson and Jonas {\AA}berg and Ruikang Tang and Sune Larsson and J{\"o}ns G Hilborn},
  journal={Acta biomaterialia},
  year={2011},
  volume={7 8},
  pages={3042-9}
}
Current treatment of fractures often involves the use of bone graft or bone morphogenetic proteins (BMP) to induce fracture healing, especially in patients with a compromised healing capacity. BMP has to be delivered in conjunction with a carrier. Unfortunately, there are drawbacks and limitations with current carriers, including their bovine origin which carries the risk of an immunological response. The physical properties also limit the use to open surgical procedures, as it cannot be… CONTINUE READING
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