Calcium permeability of neuronal nicotinic acetylcholine receptor channels in PC12 cells.

@article{Sands1991CalciumPO,
  title={Calcium permeability of neuronal nicotinic acetylcholine receptor channels in PC12 cells.},
  author={Steven B Sands and Michael E Barish},
  journal={Brain research},
  year={1991},
  volume={560 1-2},
  pages={38-42}
}
The conductance properties of neuronal nicotinic acetylcholine receptors (neuronal nAChR channels) in PC12 cells were studied using single channel and whole cell gigaohm seal voltage clamp techniques. Acetylcholine receptor agonists were applied using external pipettes. Neuronal nAChR channels were selective for monovalent cations, and were impermeable to anions. Based on measurements of shifts in reversal potential with changes in external Na and K ion concentrations and evaluation of the GHK… CONTINUE READING
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