Calcium oxalate crystal deposition in kidneys of hypercalciuric mice with disrupted type IIa sodium-phosphate cotransporter.

@article{Khan2008CalciumOC,
  title={Calcium oxalate crystal deposition in kidneys of hypercalciuric mice with disrupted type IIa sodium-phosphate cotransporter.},
  author={Saeed R Khan and Patricia A. Glenton},
  journal={American journal of physiology. Renal physiology},
  year={2008},
  volume={294 5},
  pages={F1109-15}
}
The most common theories about the pathogenesis of idiopathic kidney stones consider precipitation of calcium phosphate (CaP) within the kidneys critical for the development of the disease. We decided to test the hypothesis that a CaP substrate can promote the deposition of calcium oxalate (CaOx) in the kidneys. Experimental hyperoxaluria was induced by… CONTINUE READING