Calcium-mediated cell injury and cell death.

  title={Calcium-mediated cell injury and cell death.},
  author={Benjamin F. Trump and Irene K Berezesky},
  journal={FASEB journal : official publication of the Federation of American Societies for Experimental Biology},
  volume={9 2},
The effect of intracellular ion deregulation, particularly of [Ca2+], on the events following acute cell injury and the progression of change from initiation (reversible) to maintenance (reversible-irreversible) phases and finally to cell death has been the major thrust of experimentation in our laboratory for over 20 years. Cell death, which plays an important role in both normal and pathological phenomena, has been classified into two principal types, accidental and programmed. Recent… CONTINUE READING
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