Calcium-magnesium interactions in pancreatic acinar cells.

  title={Calcium-magnesium interactions in pancreatic acinar cells.},
  author={Frank Ch Mooren and Stefan Turi and D. Gunzel and Wolf R. Schlue and Wolfram Domschke and Jagmohan Singh and Markus M. Lerch},
  journal={FASEB journal : official publication of the Federation of American Societies for Experimental Biology},
  volume={15 3},
Although the role of calcium (Ca2+) in the signal transduction and pathobiology of the exocrine pancreas is firmly established, the role of magnesium (Mg2+) remains unclear. We have characterized the intracellular distribution of Mg2+ in response to hormone stimulation in isolated mouse pancreatic acinar cells and studied the role of Mg2+ in modulating Ca2+ signaling using microspectrofluorometry and digital imaging of Ca2+- or Mg2+-sensitive fluorescent dyes as well as Mg2+-sensitive… CONTINUE READING
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Effects of prophylactic magnesium treatment on the onset and course of acute experimental pancreatitis

  • S. Turi, V. Hlouschek, F. C. Mooren, J. Schnekenburger, Domschke, M.M.W. Lerch
  • Gastroenterology 118,
  • 2000

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