Calcium-induced calcium release contributes to somatic secretion of serotonin in leech Retzius neurons.

@article{Trueta2004CalciuminducedCR,
  title={Calcium-induced calcium release contributes to somatic secretion of serotonin in leech Retzius neurons.},
  author={Citlali Trueta and Sergio S{\'a}nchez-Arm{\'a}ss and Miguel Angel Peinado Morales and Francisco F. De-Miguel},
  journal={Journal of neurobiology},
  year={2004},
  volume={61 3},
  pages={
          309-16
        }
}
We analyzed the contribution of calcium (Ca2+)-induced Ca2+ release to somatic secretion in serotonergic Retzius neurons of the leech. Somatic secretion was studied by the incorporation of fluorescent dye FM1-43 upon electrical stimulation with trains of 10 impulses and by electron microscopy. Quantification of secretion with FM1-43 was made in cultured neurons to improve optical resolution. Stimulation in the presence of FM1-43 produced a frequency-dependent number of fluorescent spots. While… CONTINUE READING
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