Calcium handling proteins: structure, function, and modulation by exercise

  title={Calcium handling proteins: structure, function, and modulation by exercise},
  author={Jamille Locatelli and Leonardo Vin{\'i}cius Monteiro de Assis and Mauro C{\'e}sar Isoldi},
  journal={Heart Failure Reviews},
Heart failure is a serious public health issue with a growing prevalence, and it is related with the aging of the population. Hypertension is identified as the main precursor of left ventricular hypertrophy and therefore can lead to diastolic dysfunction and heart failure. Scientific studies have confirmed the beneficial effects of the physical exercise by reducing the blood pressure and improving the functional status of the heart in hypertension. Several proteins are involved in the… CONTINUE READING
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