Calcium from internal stores triggers GABA release from retinal amacrine cells.

@article{Warrier1999CalciumFI,
  title={Calcium from internal stores triggers GABA release from retinal amacrine cells.},
  author={Ajithkumar Warrier and Salvador Borges and David Dalcino and Cameron Walters and Martin Wilson},
  journal={Journal of neurophysiology},
  year={1999},
  volume={94 6},
  pages={4196-208}
}
  • Ajithkumar Warrier, Salvador Borges, +2 authors Martin Wilson
  • Published 1999 in Journal of neurophysiology
The Ca(2+) that promotes transmitter release is generally thought to enter presynaptic terminals through voltage-gated Ca(2+)channels. Using electrophysiology and Ca(2+) imaging, we show that, in amacrine cell dendrites, at least some of the Ca(2+) that triggers transmitter release comes from endoplasmic reticulum Ca(2+) stores. We show that both inositol 1,4,5-trisphosphate receptors (IP(3)Rs) and ryanodine receptors (RyRs) are present in these dendrites and both participate in the elevation… CONTINUE READING