Calcium flux across chick duodenal brush border membrane vesicles: regulation by 1,25-dihydroxyvitamin D.

@article{Bikle1983CalciumFA,
  title={Calcium flux across chick duodenal brush border membrane vesicles: regulation by 1,25-dihydroxyvitamin D.},
  author={Daniel D Bikle and Scott J Munson and David T. Zolock},
  journal={Endocrinology},
  year={1983},
  volume={113 6},
  pages={2072-80}
}
The vitamin D metabolite 1,25-dihydroxyvitamin D [1,25-(OH)2D] given in vivo stimulates calcium accumulation by subsequently isolated duodenal brush border membrane vesicles (BBMV). Stimulation is rapid (within 2 h), reaching a maximum between 2-4 h. This effect occurs well before stimulation of in vivo calcium transport (2-4 h), cytosolic calcium-binding protein production (4-8 h, or alkaline phosphatase activity (8 h). No cytosolic calcium-binding protein was found in the BBMV at any time… CONTINUE READING