Calcium extrusion from mammalian photoreceptor terminals.

  title={Calcium extrusion from mammalian photoreceptor terminals.},
  author={Catherine W. Morgans and Oussama El Far and Amy Berntson and Heinz W{\"a}ssle and W. Rowland Taylor},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  volume={18 7},
Ribbon synapses of vertebrate photoreceptors constantly release glutamate in darkness. Transmitter release is maintained by a steady influx of calcium through voltage-dependent calcium channels, implying the presence of a mechanism that is able to extrude calcium at an equal rate. The two predominant mechanisms of intracellular calcium extrusion are the plasma membrane calcium ATPase (PMCA) and the Na+/Ca2+-exchanger. Immunohistochemical staining of retina sections revealed strong… CONTINUE READING


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