Calcium entry in rabbit corneal epithelial cells: Evidence for a nonvoltage dependent pathway

@article{Rich1995CalciumEI,
  title={Calcium entry in rabbit corneal epithelial cells: Evidence for a nonvoltage dependent pathway},
  author={Alexander Rich and James L. Rae},
  journal={The Journal of Membrane Biology},
  year={1995},
  volume={144},
  pages={177-184}
}
We performed experiments to elucidate the calcium influx pathways in freshly dispersed rabbit corneal epithelial cells. Three possible pathways were considered: voltage-gated Ca++ channels, Na+/Ca++ exchange, and nonvoltage-dependent Ca++-permeable channels. Whole cell inward currents carrying either Ca++ or Ba++ were not detected using voltage clamp techniques. We also used imaging technology and the Ca++-sensitive ratiometric dye fura 2 to measure changes in intracellular Ca++ concentration… CONTINUE READING