Calcium-dependent but action potential-independent BCM-like metaplasticity in the hippocampus.

@article{Hulme2012CalciumdependentBA,
  title={Calcium-dependent but action potential-independent BCM-like metaplasticity in the hippocampus.},
  author={Sarah R. Hulme and O. D. Jones and David R. Ireland and Wickliffe C. Abraham},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2012},
  volume={32 20},
  pages={6785-94}
}
The Bienenstock, Cooper and Munro (BCM) computational model, which incorporates a metaplastic sliding threshold for LTP induction, accounts well for experience-dependent changes in synaptic plasticity in the visual cortex. BCM-like metaplasticity over a shorter timescale has also been observed in the hippocampus, thus providing a tractable experimental preparation for testing specific predictions of the model. Here, using extracellular and intracellular electrophysiological recordings from… CONTINUE READING
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References

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Synaptic homeostasis and input selectivity follow from a calcium-dependent plasticity model.

Proceedings of the National Academy of Sciences of the United States of America • 2004
View 8 Excerpts
Highly Influenced

Priming-induced shift in synaptic plasticity in the rat hippocampus.

Journal of neurophysiology • 1999
View 8 Excerpts
Highly Influenced

A model of dendritic spine Ca2+ concentration exploring possible bases for a sliding synaptic modification threshold.

Proceedings of the National Academy of Sciences of the United States of America • 1994
View 7 Excerpts
Highly Influenced

Theory for the development of neuron selectivity: orientation specificity and binocular interaction in visual cortex.

The Journal of neuroscience : the official journal of the Society for Neuroscience • 1982
View 6 Excerpts
Highly Influenced

Plasticity of calcium channels in dendritic spines

Nature Neuroscience • 2003
View 4 Excerpts
Highly Influenced

Metaplastic regulation of long-term potentiation/long-term depression threshold by activity-dependent changes of NR2A/NR2B ratio.

The Journal of neuroscience : the official journal of the Society for Neuroscience • 2009
View 1 Excerpt

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