Calcium dependence and recovery kinetics of presynaptic depression at the climbing fiber to Purkinje cell synapse.

@article{Dittman1998CalciumDA,
  title={Calcium dependence and recovery kinetics of presynaptic depression at the climbing fiber to Purkinje cell synapse.},
  author={Jeremy S. Dittman and Wade G Regehr},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={1998},
  volume={18 16},
  pages={6147-62}
}
Short-term depression is a widespread form of use-dependent plasticity found in the peripheral and central nervous systems of invertebrates and vertebrates. The mechanism behind this transient decrease in synaptic strength is thought to be primarily the result of presynaptic "depletion" of a readily releasable neurotransmitter pool, which typically recovers with a time constant of a few seconds. We studied the mechanism and dynamics of recovery from depression at the climbing fiber to Purkinje… CONTINUE READING
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