Calcium decrease associated with aminopyridine-induced potassium increase in cat cerebellum.

@article{Nicholson1976CalciumDA,
  title={Calcium decrease associated with aminopyridine-induced potassium increase in cat cerebellum.},
  author={Charles Nicholson and R{\'e}gis Steinberg and Harry Stoeckle and Gerrit ten Bruggencate},
  journal={Neuroscience letters},
  year={1976},
  volume={3 5-6},
  pages={315-9}
}
Ca(2+)- and K(+)-selective micropipettes were paired to measure extracellular ion changes in cat cerebellum superfused with aminopyridine-Ringer solution. A single shock to the cerebellar surface evoked a large transient Ca(2+) decrease and K(+) increase. Spatially, the ion changes were unequal, with the Ca(2+) decrease localized in the synaptically active region. The ion changes were reversibly abolished when citrate was added to the superfusate. The ion transients are comparable to those in… CONTINUE READING