Calcium cycling proteins and forcefrequency relationship in heart failure

@article{Hasenfuss1996CalciumCP,
  title={Calcium cycling proteins and forcefrequency relationship in heart failure},
  author={Gerd Hasenfuss and Hans Reinecke and Roland Studer and Burkert Pieske and Markus Meyer and Helmut Drexler and Hanjorg Just},
  journal={Basic Research in Cardiology},
  year={1996},
  volume={91},
  pages={17-22}
}
Myocardial function, intracellular calcium and levels of calcium cycling proteins were analyzed in failing and nonfailing human myocardium. Myocardial function was evaluated by the isometric force-frequency relation, and intracellular calcium was studied by aequorin light emission. When stimulation frequency was increased above 30 min−1, there was a continuous increase in isometric tension development in the nonfailing myocardium. In contrast, in failing myocardium, frequency potentiation of… CONTINUE READING