Calcium currents in aged rat dorsal root ganglion neurones.

  title={Calcium currents in aged rat dorsal root ganglion neurones.},
  author={Platon Grigor’evich Kostyuk and Nina Pronchuk and Arina N. Savchenko and Alexej N. Verkhratsky},
  journal={The Journal of physiology},
1. The whole-cell voltage clamp technique was used to record calcium currents in the somatic membrane of rat cultured dorsal root ganglion neurones. 2. Neurones were enzymatically isolated from animals of three age groups (neonatal, 2-7 days; adult, 7 months; and old, 30 months) and maintained in primary culture 3-14 days. 3. The neurones isolated from neonatal and old rats showed two distinct types of Ca2+ currents, a low-threshold transient current and a high-threshold sustained current… CONTINUE READING
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