Calcium current modulation in frog sympathetic neurones: L-current is relatively insensitive to neurotransmitters.

@article{Elmslie1992CalciumCM,
  title={Calcium current modulation in frog sympathetic neurones: L-current is relatively insensitive to neurotransmitters.},
  author={Keith Elmslie and Paul J. Kammermeier and Stephen W. Jones},
  journal={The Journal of physiology},
  year={1992},
  volume={456},
  pages={107-23}
}
1. Neurotransmitters (noradrenaline, NA; chicken II luteinizing hormone-releasing hormone, LHRH) and activators of G proteins (GTP-gamma-S and AlF3) partially inhibit calcium current in bullfrog sympathetic neruones. Activation of the remaining current is slowed and shifted to more positive voltages. 2. The N-type calcium current appears to be the type modulated, since approximately 90% of peak current is blocked by omega-conotoxin (omega CgTx) and modulation is not affected by nisoldipine. 3… CONTINUE READING

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