Calcium channels in smooth muscle cells from cerebral precapillary arterioles activate at more negative potentials than those from basilar artery

@article{Michelakis1994CalciumCI,
  title={Calcium channels in smooth muscle cells from cerebral precapillary arterioles activate at more negative potentials than those from basilar artery},
  author={Evangelos D Michelakis and Kirti Tewari and J. Marc Simard},
  journal={Pfl{\"u}gers Archiv},
  year={1994},
  volume={426},
  pages={459-461}
}
We compared Ca2+ channels in cell-attached patches of smooth muscle cells from cerebral precapillary arterioles and basilar artery of guinea pig. Patches were studied without Ca2+ channel activators in the pipette solution. In both preparations, a 23 pS channel (40 mM Ba2+) sensitive to block by nifedipine was identified. In arteriolar but not in basilar artery patches, channel activity was recorded without apparent inactivation at potentials of −40 to −20 mV. Values for the number of channels… CONTINUE READING