Calcium channels in planar lipid bilayers: insights into mechanisms of ion permeation and gating.

Abstract

Electrophysiological recordings were used to analyze single calcium channels in planar lipid bilayers after membranes from bovine cardiac sarcolemmal vesicles had been incorporated into the bilayer. In these cell-free conditions, channels in the bilayer showed unitary barium or calcium conductances, gating kinetics, and pharmacological responses that were… (More)

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@article{Rosenberg1986CalciumCI, title={Calcium channels in planar lipid bilayers: insights into mechanisms of ion permeation and gating.}, author={R. L. Rosenberg and Phil Hess and John P. Reeves and Henry M. Smilowitz and Richard W. Tsien}, journal={Science}, year={1986}, volume={231 4745}, pages={1564-6} }