Calcium channels and calcium-gated potassium channels at the frog neuromuscular junction.

@article{Robitaille1993CalciumCA,
  title={Calcium channels and calcium-gated potassium channels at the frog neuromuscular junction.},
  author={Richard Robitaille and Elizabeth M Adler and Milton P. Charlton},
  journal={Journal of physiology, Paris},
  year={1993},
  volume={87 1},
  pages={15-24}
}
Two mechanisms which regulate transmitter release by regulating Ca2+ entry in the presynaptic nerve terminal were studied at the frog neuromuscular junction (nmj). First, the location of Ca2+ channels in relation to transmitter release sites and, second, the regulation of Ca2+ entry by Ca(2+)-gated potassium (gKca) channels. Ca2+ channels were disclosed using fluorescent omega-conotoxin GVIA (omega-CgTX) which blocks transmitter release and Ca2+ entry at the frog nmj. Ca2+ channels were located… CONTINUE READING

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