Calcium channel modulation by β-adrenergic neurotransmitters in the heart

Abstract

Calcium ions play a crucial role in the regulation of the heart beat. During each action potential Ca2+ ions flow into the cell and are directly and indirectly involved in generation of pacemaker potentials and of contractile force. Adrenergic and cholinergic neurotransmitters modulate Ca2+ influx. The most detailed analysis has been made on the mechanism of the β-adrenergic effect on calcium channels in cardiac cell membranes. This is briefly summarized in a personal account, while for more detailed information the reader is referred to more extensive recent reviews16, 22.

DOI: 10.1007/BF01945518

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Cite this paper

@article{Reuter2005CalciumCM, title={Calcium channel modulation by β-adrenergic neurotransmitters in the heart}, author={Henry Reuter}, journal={Experientia}, year={2005}, volume={43}, pages={1173-1175} }