Calcium-channel drugs: structure-function relationships and selectivity of action.

Abstract

Calcium channels are ubiquitously distributed in excitable cells. The calcium-channel antagonists interact specifically at the L subclass of channels to mediate cardiovascular effects. These channels may be considered as pharmacologic receptors with specific drug binding sites and subject to a variety of regulatory influences. Each site is specific for… (More)

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Cite this paper

@article{Triggle1991CalciumchannelDS, title={Calcium-channel drugs: structure-function relationships and selectivity of action.}, author={David J. Triggle}, journal={Journal of cardiovascular pharmacology}, year={1991}, volume={18 Suppl 10}, pages={S1-6} }