Calcium channel blockers inhibit galvanotaxis in human keratinocytes.

  title={Calcium channel blockers inhibit galvanotaxis in human keratinocytes.},
  author={Donna R Trollinger and Roslyn Rivkah Isseroff and Richard L Nuccitelli},
  journal={Journal of cellular physiology},
  volume={193 1},
Directed migration of keratinocytes is essential for wound healing. The migration of human keratinocytes in vitro is strongly influenced by the presence of a physiological electric field and these cells migrate towards the negative pole of such a field (galvanotaxis). We have previously shown that the depletion of extracellular calcium blocks the directional migration of cultured human keratinocytes in an electric field (Fang et al., 1998; J Invest Dermatol 111:751-756). Here we further… CONTINUE READING

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