• DOI:10.3233/JAD-2012-111664
Corpus ID: 25958438

Calcium channel blockers and Alzheimer's disease: potential relevance in treatment strategies of metabolic syndrome.

@article{Goodison2012CalciumCB,
  title={Calcium channel blockers and Alzheimer's disease: potential relevance in treatment strategies of metabolic syndrome.},
  author={William V Goodison and V. Frisardi and P. Kehoe},
  journal={Journal of Alzheimer's disease : JAD},
  year={2012},
  volume={30 Suppl 2},
  pages={
          S269-82
        }
}

William V Goodison, V. Frisardi, P. Kehoe

Published 2012

Medicine

Journal of Alzheimer's disease : JAD

Midlife hypertension is a risk factor for late onset Alzheimer's disease (AD) and it is one of the components of metabolic syndrome (MetS). Observational studies and some cardiovascular disease-related clinical trials suggest that antihypertensive treatment reduced the incidence and progression of AD. Calcium channel blockers (CCBs), one of the more commonly used treatments for hypertension, target voltage-gated calcium channels (VGCCs) which are found on neurons in the brain where calcium… CONTINUE READING

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