Calcium channel blockade blunts the renal effects of acute nitric oxide synthase inhibition in healthy humans.

Abstract

Our aim was to investigate whether blockade of calcium channels (CCs) or angiotensin II type 1 receptors (AT1R) modulates renal responses to nitric oxide synthesis inhibition (NOSI) in humans. Fourteen sodium-replete, healthy volunteers underwent 90-min infusions of 3.0 μg·kg-1·min-1 NG-nitro-l-arginine methyl ester (l-NAME) on 3 occasions, preceded by 3… (More)
DOI: 10.1152/ajprenal.00568.2016

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Cite this paper

@article{Montanari2017CalciumCB, title={Calcium channel blockade blunts the renal effects of acute nitric oxide synthase inhibition in healthy humans.}, author={Alberto Montanari and Davide Lazzeroni and Giovanna M Pel{\`a} and Antonio Crocamo and Yuliya Lytvyn and Luisa Musiari and Aderville Cabassi and David Z I Cherney}, journal={American journal of physiology. Renal physiology}, year={2017}, volume={312 5}, pages={F870-F878} }