Calcium channel antagonists in the management of anginal syndromes: changing concepts in relation to the role of coronary vasospasm.

@article{Opie1996CalciumCA,
  title={Calcium channel antagonists in the management of anginal syndromes: changing concepts in relation to the role of coronary vasospasm.},
  author={Lionel Henry Opie},
  journal={Progress in cardiovascular diseases},
  year={1996},
  volume={38 4},
  pages={291-314}
}
Despite the increasing evidence that alterations in coronary vascular tone can and do occur in patients with anginal syndromes, only in a minority of such patients with Prinzmetal's angina is there decisive evidence that the coronary vasodilation induced by calcium channel antagonists (CCAs) plays a specific therapeutic role. CCAs may also give therapeutic benefit in a number of conditions in which coronary vasoconstriction may contribute to ischemia, such as hyperventilation, cold-induced… CONTINUE READING

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