Calcium channel antagonists and renin release.

Abstract

Calcium (Ca2+) is an inhibitory second messenger in the renin secretory process, and evidence suggests that first messengers can alter Ca2+ in the renin-secreting juxtaglomerular cells by altering Ca2+ influx, efflux, and mobilization pathways. Influx of Ca2+ through voltage-operated channels is one such pathway, and it has been suggested that pressure… (More)

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