Calcium channel alpha2delta subunits: differential expression, function, and drug binding.

@article{Klugbauer2003CalciumCA,
  title={Calcium channel alpha2delta subunits: differential expression, function, and drug binding.},
  author={Norbert Klugbauer and Els{\'e} Marais and Franz Hofmann},
  journal={Journal of bioenergetics and biomembranes},
  year={2003},
  volume={35 6},
  pages={639-47}
}
Voltage-activated calcium channels are transmembrane proteins that act as transducers of electrical signals into numerous intracellular activities. On the basis of their electrophysiological properties they are classified as high- and low-voltage-activated calcium channels. High-voltage-activated calcium channels are heterooligomeric proteins consisting of a pore-forming alpha1 subunit and auxiliary alpha2delta, beta, and--in some tissues--gamma subunits. Auxiliary subunits support the membrane… CONTINUE READING

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