Calcium carbonate breath test for non-invasive estimation of gastric acid secretion.

@article{Shinkai2014CalciumCB,
  title={Calcium carbonate breath test for non-invasive estimation of gastric acid secretion.},
  author={Hirohiko Shinkai and Katsunori Iijima and Tomoyuki Koike and Kenichiro Nakagawa and Ryuhei Maejima and Hiroyuki Endo and Nobuyuki Ara and Naoki Asano and Akira Imatani and Shuichi Ohara and Tooru Shimosegawa},
  journal={The Tohoku journal of experimental medicine},
  year={2014},
  volume={232 4},
  pages={
          255-61
        }
}
Gastric acid measurement is useful in assessing the effectiveness of antisecretory drugs, however, the conventional tests involve invasive nasogastric intubation. Orally administered ¹³C-labeled calcium carbonate (Ca¹³CO₃) reacts with gastric acid to produce ¹³C-labeled carbon dioxide (¹³CO₂), which is then excreted in the breath. The objective of this study was to evaluate the suitability of Ca¹³CO3 breath test for estimating gastric acid secretion in human noninvasively. First, the Ca¹³CO… CONTINUE READING

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