Calcium-binding protein S100P and cancer: mechanisms and clinical relevance


S100P is a 95-amino-acid protein and a member of the S100 family. It was first purified from placenta. The promoter area of S100P has binding sites for SMAD, STAT/CREB and SP/KLF, key regulatory elements participating in transcriptional activation of the S100P gene. Increased levels of S100P have been observed in multiple tumor cell lines and breast… (More)
DOI: 10.1007/s00432-011-1062-5


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