Calcium antagonists in geriatric patients: diltiazem in elderly persons with hypertension.

@article{Montamat1989CalciumAI,
  title={Calcium antagonists in geriatric patients: diltiazem in elderly persons with hypertension.},
  author={Stephen C Montamat and Darrell R. Abernethy},
  journal={Clinical pharmacology and therapeutics},
  year={1989},
  volume={45 6},
  pages={682-91}
}
Pharmacodynamics and disposition of diltiazem were determined in twelve young (30 to 39 years of age) and twelve elderly (65 to 83 years of age) persons with hypertension after they had received diltiazem by rapid intravenous and long-term oral administration. Plasma disappearance half-life of diltiazem increased similarly and significantly in both groups… CONTINUE READING