Calcium- and voltage-activated potassium channels in human macrophages.

  title={Calcium- and voltage-activated potassium channels in human macrophages.},
  author={Elaine K. Gallin},
  journal={Biophysical journal},
  volume={46 6},
Single calcium-activated potassium channel currents were recorded in intact and excised membrane patches from cultured human macrophages. Channel conductance was 240 pS in symmetrical 145 mM K+ and 130 pS in 5 mM external K+. Lower conductance current fluctuations (40% of the larger channels) with the same reversal potential as the higher conductance channels were noted in some patches. Ion substitution experiments indicated that the channel is permeable to potassium and relatively impermeable… CONTINUE READING

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