Calcium and vitamin D metabolism in acromegaly.

  title={Calcium and vitamin D metabolism in acromegaly.},
  author={Bj. Lund and Peter C Eskildsen and Anthony W. Norman and Ole Helmer S\orensen},
  journal={Acta endocrinologica},
  volume={96 4},
Acromegalic subjects were found to have elevated serum levels of both 1,25-dihydroxyvitamin D (1,25-(OH)2D), 67 +/- 22 (SD) pg/ml) and 24.25-dihydroxyvitamin D (24.25-(OH)2D), (6.9 +/- 1.5 (SD) ng/ml). The serum concentration of 1,25-(OH)2D correlated positively (P less than 0.02, R = 0.56) to the 24 h urinary excretion of growth hormone, but not to the serum levels of parathyroid hormone, prolactin, thyroid hormones or the urinary excretion of free cortisol. Fourteen patients were treated with… CONTINUE READING